SCHEMBL7659967

SCHEMBL7659967

CCCCOc1ccc2c(ccc3cc(OC(F)(F)F)ccc32)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
PPM1A P35813 3/20 0.43
PDK2 Q15119 3/20 0.41
FFAR4 Q5NUL3 2/20 0.40
MAOB P27338 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
KIF11 P52732 1/20 0.39
FFAR1 O14842 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7665021 0.97 PDK2 (0.43) CA12CA1CA2CA3CA4
SCHEMBL7658329 0.96 PDK2 (0.44) CA12CA1CA2CA3CA4
SCHEMBL7661606 0.94 CA12 (0.43) CA12CA1CA2CA3CA4
SCHEMBL7658885 0.87 L3MBTL1 (0.47) CA12CA1CA4CA6CA7
SCHEMBL16519478 0.85 CA12 (0.51) CA12CA1CA2CA3CA4
SCHEMBL7655968 0.84 PCSK9 (0.43) PPM1AHDAC3HDAC1HDAC2KIF11
SCHEMBL7655752 0.83 PDE2A (0.43) CA12CA1CA2CA3CA4
SCHEMBL7661620 0.82 PPARG (0.40) PPM1A
SCHEMBL20432126 0.82 TSHR (0.50) PDK2
SCHEMBL8724311 0.82 NR5A1 (0.55) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6495220-B2 WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS CLARIANT INTERNATIONAL LTD. (CH) 2002-12-17 US disclosed
US-20010023935-A1 With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers CLARIANT INTERNATIONAL LTD. (CH) 2001-09-27 US disclosed