Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.40 |
| ▸ | MIF | P14174 | 6/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.40 |
| ▸ | ITGAM | P11215 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530409 | 0.90 | ITGB3 (0.43) | ITGB3ITGA2BMIFITGB2ITGAM | |
| SCHEMBL7525600 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BMIFITGB2ITGAM | |
| SCHEMBL7527828 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BMIFITGB2ITGAM | |
| SCHEMBL7534732 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BMIFITGB2ITGAM | |
| SCHEMBL7528978 | 0.82 | MAPT (0.48) | ITGB3ITGA2BMIFITGB2ITGAM | |
| SCHEMBL7536611 | 0.81 | ITGB3 (0.58) | ITGB3ITGA2BITGB2ITGAMF2 | |
| SCHEMBL7532685 | 0.81 | AR (0.41) | ITGB3ITGA2BMIFITGB2ITGAM | |
| SCHEMBL7660015 | 0.80 | MIF (0.39) | ITGB3ITGA2BMIFHDAC6 | |
| SCHEMBL7532410 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2BMIFITGB2ITGAM | |
| SCHEMBL7522105 | 0.79 | ALDH1A1 (0.42) | ITGB3ITGA2BMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476226-B2 | PLATELET GLYCOPROTEIN IIB/IIIA FIBRINOGEN; ANTICOAGULANTS; THROMBOLYTIC AGENTS; THROMBOEMBOLIC DISORDERS; ANTIINFLAMMATORY AGENTS; BONE DISORDERS; ANTITUMOR, -METASTASIS, -ARTHRITIC AGENTS; ASTHMA; PSORIASIS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-11-05 | — | — | US | disclosed |
| US-6303609-B1 | USED FOR THE INHIBITION OF PLATELET AGGREGATION, AS THROMBOLYTICS, AND/OR FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2001-10-16 | — | — | US | disclosed |