Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663129 | 0.81 | APOBEC3G (0.41) | ALDH1A1MMP13MMP1 | |
| SCHEMBL7672556 | 0.81 | NAAA (0.39) | MAPTNPC1ALDH1A1POLBGAA | |
| SCHEMBL7672017 | 0.80 | NPC1 (0.42) | NPC1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL7660479 | 0.78 | MAPT (0.44) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7665567 | 0.72 | MAPT (0.42) | MAPTFAAHALDH1A1KDM4EKMT2A | |
| SCHEMBL8064604 | 0.71 | ALDH1A1 (0.46) | MAPTNPC1FAAHALDH1A1KDM4E | |
| SCHEMBL24333942 | 0.71 | NPC1 (0.53) | MAPTNPC1ALDH1A1KDM4EKMT2A | |
| SCHEMBL20495584 | 0.69 | NPC1 (0.46) | NPC1ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL24333928 | 0.69 | NPC1 (0.46) | NPC1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL4202023 | 0.69 | PSEN1 (0.43) | MAPTPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348614-B1 | PROTECTING CROPS AGAINST PLANT DISEASES | AGROGENE LTD. (IL) | 2002-02-19 | — | — | US | claimed |
| EP-0948481-A1 | AMINOBUTYRIC ACID FUNGICIDES | Agrogene Ltd. (IL) | 1999-10-13 | — | — | EP | claimed |
| WO-1998029387-A1 | AMINOBUTYRIC ACID FUNGICIDES | AGROGENE LTD. (IL) | 1998-07-09 | — | — | WO | claimed |
| US-6348614-B1 | PROTECTING CROPS AGAINST PLANT DISEASES | AGROGENE LTD. (IL) | 2002-02-19 | — | — | US | disclosed |
| EP-0948481-A1 | AMINOBUTYRIC ACID FUNGICIDES | Agrogene Ltd. (IL) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998029387-A1 | AMINOBUTYRIC ACID FUNGICIDES | AGROGENE LTD. (IL) | 1998-07-09 | — | — | WO | disclosed |