Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193682 | 0.91 | EGFR (0.69) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL7711919 | 0.90 | EGFR (0.52) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL7471413 | 0.89 | EGFR (0.58) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL9435935 | 0.86 | EGFR (0.52) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL7462603 | 0.84 | EGFR (0.60) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL28471467 | 0.83 | NR1H4 (0.57) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL11980711 | 0.82 | EGFR (0.63) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL28280620 | 0.82 | EGFR (0.58) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL29763168 | 0.82 | HDAC6 (0.53) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL1066049 | 0.82 | EGFR (0.49) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603647-B | PARP inhibitor-alkylation bifunctional molecule and preparation method and application thereof | 潍坊医学院 | 2023-01-31 | — | — | CN | claimed |
| CN-112979744-B | Diosgenin mosaic nitrogen mustard derivative with anti-tumor activity and preparation method and application thereof | 齐齐哈尔医学院 | 2022-02-15 | — | — | CN | claimed |
| CN-113603647-A | PARP inhibitor-alkylation bifunctional molecule and preparation method and application thereof | 潍坊医学院 | 2021-11-05 | — | — | CN | claimed |
| EP-0408546-B1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS | CANCER RES CAMPAIGN TECH (GB) | 1994-04-27 | — | — | EP | claimed |
| CN-118878468-B | Diamino pyrimidine compound containing phenyl nitrogen mustard fragment and preparation method and application thereof | 贵州大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-119192193-A | Oridonin derivative and preparation method and application thereof | 深圳职业技术大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-119039281-A | Preparation method and application of luteolin nitrogen mustard derivative | 黑龙江八一农垦大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-118878468-A | Diamino pyrimidine compound containing phenyl nitrogen mustard fragment and preparation method and application thereof | 贵州大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-113979954-B | Tinich antitumor drug compound and preparation method and application thereof | 南京友怡医药科技有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-115925712-B | Targeted antitumor drug compound and preparation method and application thereof | 南京友怡医药科技有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-115925712-A | Targeted antitumor drug compound and preparation method and application thereof | 南京友怡医药科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113603647-B | PARP inhibitor-alkylation bifunctional molecule and preparation method and application thereof | 潍坊医学院 | 2023-01-31 | — | — | CN | disclosed |
| WO-1990015819-A1 | IRREVERSIBLE BOMBESIN ANTAGONISTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-12-27 | — | — | WO | disclosed |
| EP-0402852-A1 | Irreversible bombesin antagonists | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-12-19 | — | — | EP | disclosed |
| US-4938897-A | Chlorambucil derivatives and cell-discriminating agent containing the same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0208446-B1 | FLUORESCENT SUBSTANCE FOR USE AS A CELL-DISCRIMINATING AGENT | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-03-14 | — | — | EP | disclosed |
| WO-1989010140-A1 | FURTHER IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1989-11-02 | — | — | WO | disclosed |
| EP-0208446-A1 | Fluorescent substance for use as a cell-discriminating agent | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-01-14 | — | — | EP | disclosed |
| US-4181669-A | A CARBODIIMIDE WITH ACID CATALYSTS AS A CONDENSATION AGENT | AKTIEBOLAGET LEO (SE) | 1980-01-01 | — | — | US | disclosed |
| US-4180504-A | Method for the preparation of esters | AKTIEBOLAGET LEO (SE) | 1979-12-25 | — | — | US | disclosed |