Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435956 | 0.92 | SMN1; SMN2 (0.45) | EGFRERBB2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL766052 | 0.86 | EGFR (0.61) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL1066049 | 0.82 | EGFR (0.49) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL8193682 | 0.81 | EGFR (0.69) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL7471413 | 0.80 | EGFR (0.58) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL3646979 | 0.79 | EGFR (0.46) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL8724096 | 0.78 | ALDH1A1 (0.50) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL8724095 | 0.78 | EGFR (0.39) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL8813952 | 0.77 | ALOX5 (0.45) | EGFRERBB2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7711919 | 0.77 | EGFR (0.52) | EGFRERBB2SMN1; SMN2ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408546-B1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS | CANCER RES CAMPAIGN TECH (GB) | 1994-04-27 | — | — | EP | claimed |
| EP-0408546-A1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS. | CANCER RES CAMPAIGN TECH (GB) | 1991-01-23 | — | — | EP | claimed |
| WO-1988007378-A1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LTD. (GB) | 1988-10-06 | — | — | WO | claimed |