Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.45 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650550 | 0.82 | MGLL (0.44) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7653357 | 0.81 | ABHD16A (0.48) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL7046511 | 0.78 | ABHD16A (0.57) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL2233406 | 0.76 | ABHD16A (0.72) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7044315 | 0.73 | MGLL (0.62) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6601668 | 0.72 | ABHD16A (0.54) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7043167 | 0.71 | MGLL (0.56) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7044439 | 0.71 | MGLL (0.78) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7045595 | 0.71 | MGLL (0.51) | MGLLFAAHABHD16ALMNA | |
| SCHEMBL7043178 | 0.71 | ABHD16A (0.59) | MGLLFAAHABHD16ALPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369088-B2 | ANTIDIABETIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |
| US-20010031772-A1 | Substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones, their preparation and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031772-A1 | Substituted 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-ones, their preparation and their use as pharmaceuticals | CNR1, PTGER1, CNR2 | MGLL 1542/4885FAAH 46/4885ABHD16A 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.