SCHEMBL2233406

SCHEMBL2233406

COc1nn(-c2ccc(Cl)cc2)c(=O)o1

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABHD16A O95870 2/20 0.72
MGLL Q99685 5/20 0.65
FAAH O00519 4/20 0.65
LPL P06858 1/20 0.52
LIPC P11150 1/20 0.52
LIPE Q05469 1/20 0.52
POLB P06746 1/20 0.46
NPBWR1 P48145 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7044439 0.93 MGLL (0.78) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL2853266 0.86 MGLL (0.64) ABHD16AMGLLFAAHNPBWR1
SCHEMBL2235103 0.85 ABHD16A (0.74) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL7044319 0.84 ABHD16A (0.53) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL2233598 0.84 ABHD16A (0.72) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL7046228 0.84 ABHD16A (0.72) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL11620781 0.83 FAAH (0.78) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL6551854 0.81 FAAH (0.74) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL7043932 0.81 LPL (0.56) ABHD16AMGLLFAAHLPLLIPC
SCHEMBL7578034 0.81 ABHD16A (0.68) ABHD16AMGLLFAAHLPLLIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299264-B2 Method for producing oxadiazolinone compound and intermediate thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-20110207936-A1 METHOD FOR PRODUCING OXADIAZOLINONE COMPOUND AND INTERMEDIATE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-25 US disclosed
EP-2357167-A1 METHOD FOR PRODUCING OXADIAZOLINONE COMPOUND AND INTERMEDIATE THEREOF Sumitomo Chemical Company, Limited (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207936-A1 METHOD FOR PRODUCING OXADIAZOLINONE COMPOUND AND INTERMEDIATE THEREOF AHR, CYP1B1, AR ABHD16A 3723/4885MGLL 4777/4885FAAH 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.