Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012470 | 0.84 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BGAAMAPT | |
| SCHEMBL7013687 | 0.84 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BGAAMAPT | |
| SCHEMBL7005481 | 0.79 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BGAAMAPT | |
| SCHEMBL7013446 | 0.77 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BKMT2A | |
| Potassium Ion SCHEMBL7666970 | 0.75 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL7014096 | 0.75 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BMAPT | |
| Abanoquil SCHEMBL528781 | 0.73 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BKMT2AMAOB | |
| SCHEMBL7011426 | 0.73 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BGAAMAPT | |
| SCHEMBL6764961 | 0.73 | ADRB1 (0.45) | MAPTALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL7014166 | 0.72 | ADRA1D (0.45) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365599-B1 | FOR THERAPY OF BENIGN PROSTATIC HYPERPLASIA | PFIZER, INC. | 2002-04-02 | — | — | US | disclosed |