Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661532 | 1.00 | KDM4E (0.55) | KDM4EMAPK1THRBATMCA12 | |
| SCHEMBL22076567 | 0.81 | ALDH1A1 (0.47) | TYRSTAT3ALDH1A1RAB9A | |
| SCHEMBL6862384 | 0.77 | KCNA5 (0.51) | KDM4ESMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL3978916 | 0.77 | KCNA5 (0.51) | KDM4ESMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL6910158 | 0.77 | KCNA5 (0.51) | KDM4ESMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL10903828 | 0.77 | KDM4E (0.60) | KDM4EMAPK1THRBATMCA12 | |
| SCHEMBL4486192 | 0.76 | TAAR1 (0.52) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL28827835 | 0.76 | MAPT (0.47) | STAT3SMN1; SMN2ALDH1A1ACHERAB9A | |
| SCHEMBL14042112 | 0.76 | TAAR1 (0.52) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL4484678 | 0.76 | TAAR1 (0.52) | KDM4ECA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413995-B1 | IMMUNOMODULATORS | TSUMURA & CO. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1142875-A1 | CINNAMAMIDE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | TSUMURA & CO. (JP) | 2001-10-10 | — | — | EP | disclosed |