Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7661980 | 0.87 | NAMPT (0.42) | NAMPTALOX15TSHRKDM4EUSP2 | |
| SCHEMBL7011928 | 0.82 | CYP3A4 (0.46) | NAMPTALOX15TSHRCYP1A2CYP3A4 | |
| SCHEMBL7657342 | 0.82 | CA1 (0.52) | ALOX15TSHRKDM4EUSP2POLB | |
| SCHEMBL7650969 | 0.78 | ALOX15 (0.53) | ALOX15TSHRKDM4EUSP2POLB | |
| SCHEMBL7658197 | 0.78 | ALOX15 (0.53) | ALOX15TSHRKDM4EUSP2POLB | |
| SCHEMBL7653307 | 0.77 | KDM4E (0.59) | ALOX15TSHRKDM4EUSP2POLB | |
| SCHEMBL18118206 | 0.75 | CHRNA7 (0.50) | NAMPTALOX15TSHRCYP1A2CYP3A4 | |
| SCHEMBL27524682 | 0.73 | CYP1A2 (0.43) | ALOX15TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9594739 | 0.72 | NOTUM (0.61) | ALOX15TSHRCYP3A4CYP2D6KMT2A | |
| SCHEMBL28823760 | 0.71 | CYP3A4 (0.47) | NAMPTALOX15HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |