Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.68 |
| ▸ | FNTB | P49356 | 18/20 | 0.68 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | NRAS | P01111 | 1/20 | 0.50 |
| ▸ | HRAS | P01112 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657803 | 0.87 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7593695 | 0.81 | FNTA (0.59) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7548991 | 0.79 | CYP11B1 (0.64) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7747228 | 0.78 | CYP11B1 (0.62) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7592794 | 0.77 | FNTA (0.67) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7590272 | 0.76 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7665146 | 0.76 | FNTA (0.73) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7591010 | 0.76 | FNTA (0.58) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7528653 | 0.74 | FNTA (0.63) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8005220 | 0.74 | FNTA (0.62) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335343-B1 | IMIDAZOL-5-YLALKYLPIPERIZINE DERIVATIVES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-01-01 | — | — | US | claimed |
| US-6335343-B1 | IMIDAZOL-5-YLALKYLPIPERIZINE DERIVATIVES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-01-01 | — | — | US | disclosed |