Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161415 | 0.84 | MAPK1 (0.58) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7778713 | 0.82 | RAB9A (0.67) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7848400 | 0.81 | RAB9A (0.66) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL6811107 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL7848327 | 0.78 | RAB9A (0.69) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7165787 | 0.78 | ALDH1A1 (0.62) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL6814972 | 0.78 | NPC1 (0.57) | RAB9ANPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL6814915 | 0.77 | ALDH1A1 (0.60) | RAB9ANPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL7165968 | 0.77 | MEN1 (0.76) | RAB9ANPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL7662848 | 0.76 | RAB9A (0.81) | RAB9ANPC1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403617-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMANHERPESVIRUSES-6 AND -7, AND KAPOSI HERPESVIRUS | AMERICAN HOME PRODUCTS CORP. | 2002-06-11 | — | — | US | disclosed |