Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 14/20 | 0.34 |
| ▸ | QPCT | Q16769 | 12/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661618 | 0.91 | PDE4B (0.38) | GSK3BQPCTIDH1 | |
| SCHEMBL7653994 | 0.91 | CAMK2D (0.43) | CAMK2DGSK3B | |
| SCHEMBL7652581 | 0.88 | CAMK2D (0.41) | CAMK2DGSK3B | |
| SCHEMBL7662836 | 0.87 | GSK3B (0.32) | GSK3BQPCT | |
| SCHEMBL7661596 | 0.87 | IGF1R (0.35) | CAMK2DMAPT | |
| SCHEMBL7658179 | 0.86 | CAMK2D (0.33) | CAMK2DMAPT | |
| SCHEMBL7662871 | 0.85 | CAMK2D (0.40) | CAMK2DDYRK1AGSK3BQPCTMEN1 | |
| SCHEMBL7664757 | 0.85 | CAMK2D (0.38) | CAMK2DDYRK1AGSK3BQPCTMEN1 | |
| SCHEMBL7657255 | 0.84 | MAPT (0.34) | CAMK2DGSK3BQPCTMEN1MAPT | |
| SCHEMBL7654501 | 0.84 | MEN1 (0.32) | CAMK2DGSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | disclosed |