Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653994 | 0.87 | CAMK2D (0.43) | CAMK2DGSK3B | |
| SCHEMBL7657012 | 0.86 | MAPT (0.36) | MAPTASH1LHTTALDH1A1TDP1 | |
| SCHEMBL7654047 | 0.86 | ASH1L (0.35) | MAPTASH1LTDP1CAMK2DGSK3B | |
| SCHEMBL7652581 | 0.85 | CAMK2D (0.41) | CAMK2DGSK3B | |
| SCHEMBL7663240 | 0.84 | CAMK2D (0.38) | MAPTHTTMEN1KMT2ACAMK2D | |
| Acetic Acid SCHEMBL7657005 | 0.84 | MAPT (0.37) | MAPTASH1LTDP1MEN1KMT2A | |
| Acetic Acid SCHEMBL7815326 | 0.84 | MAPT (0.41) | MAPTASH1LL3MBTL1POLBALDH1A1 | |
| SCHEMBL7661373 | 0.84 | TRPM8 (0.34) | MAPTALDH1A1CAMK2DSMN1; SMN2 | |
| Acetic Acid SCHEMBL7657247 | 0.84 | ASH1L (0.37) | MAPTASH1LGAAALDH1A1TDP1 | |
| Acetic Acid SCHEMBL8366763 | 0.83 | MAPT (0.38) | MAPTASH1LGAAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | disclosed |