Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664008 | 1.00 | HIF1A (0.49) | HIF1ATP53HTTMAPTTDP1 | |
| SCHEMBL8618320 | 0.92 | HIF1A (0.49) | HIF1ATP53HTTMAPTTDP1 | |
| SCHEMBL8618319 | 0.92 | HIF1A (0.49) | HIF1ATP53HTTMAPTTDP1 | |
| SCHEMBL8781729 | 0.89 | HIF1A (0.50) | HIF1ATP53HTTMAPTTDP1 | |
| SCHEMBL6899784 | 0.89 | HIF1A (0.51) | HIF1ATP53HTTMAPTTDP1 | |
| SCHEMBL435570 | 0.89 | HIF1A (0.51) | HIF1ATP53HTTMAPTTDP1 | |
| SCHEMBL435569 | 0.89 | HIF1A (0.51) | HIF1ATP53HTTMAPTTDP1 | |
| SCHEMBL8618566 | 0.89 | HIF1A (0.56) | HIF1ATP53HTTRXRA | |
| SCHEMBL8618563 | 0.89 | HIF1A (0.56) | HIF1ATP53HTTRXRA | |
| SCHEMBL8618371 | 0.89 | HIF1A (0.50) | HIF1ATP53HTTMAPTSGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407098-B1 | 3-(CARBOXIMINO)-1,4,2-OXATHIAZINE DERIVATIVES; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | disclosed |
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |