Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618566 | 1.00 | HIF1A (0.56) | HIF1ATP53HTTNPSR1SMN1; SMN2 | |
| SCHEMBL8618372 | 0.90 | HIF1A (0.50) | HIF1ATP53HTTNPSR1HPGD | |
| SCHEMBL8618371 | 0.90 | HIF1A (0.50) | HIF1ATP53HTTNPSR1HPGD | |
| SCHEMBL7664008 | 0.89 | HIF1A (0.49) | HIF1ATP53HTTRXRA | |
| SCHEMBL7664003 | 0.89 | HIF1A (0.49) | HIF1ATP53HTTRXRA | |
| SCHEMBL8624127 | 0.88 | HIF1A (0.57) | HIF1ATP53HTTSMN1; SMN2LMNA | |
| SCHEMBL8624123 | 0.88 | HIF1A (0.57) | HIF1ATP53HTTSMN1; SMN2LMNA | |
| SCHEMBL8624136 | 0.88 | HIF1A (0.57) | HIF1ATP53HTTNPSR1SMN1; SMN2 | |
| SCHEMBL8624133 | 0.88 | HIF1A (0.57) | HIF1ATP53HTTNPSR1SMN1; SMN2 | |
| SCHEMBL8619361 | 0.86 | HIF1A (0.47) | HIF1ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |