SCHEMBL435569

SCHEMBL435569

CO/N=C(/C(=O)O)c1ccccc1COc1ccccc1C

nearest known ligand 0.80

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.51
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46
TP53 P04637 1/20 0.46
HTT P42858 1/20 0.46
RECQL P46063 1/20 0.45
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.42
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435570 1.00 HIF1A (0.51) HIF1ARXRARXRBRXRGTP53
SCHEMBL6899784 1.00 HIF1A (0.51) HIF1ARXRARXRBRXRGTP53
SCHEMBL8622793 0.91 HIF1A (0.51) HIF1ATP53HTTALDH1A1MAPT
SCHEMBL8622797 0.91 HIF1A (0.51) HIF1ATP53HTTALDH1A1MAPT
SCHEMBL8781729 0.90 HIF1A (0.50) HIF1ARXRARXRBRXRGTP53
Kresoxim-Methyl SCHEMBL29356012 0.89 HIF1A (0.64) HIF1ARXRARXRBRXRGTP53
Kresoxym-Methyl SCHEMBL12920836 0.89 HIF1A (0.64) HIF1ARXRARXRBRXRGTP53
SCHEMBL7664003 0.89 HIF1A (0.49) HIF1ARXRARXRBRXRGTP53
SCHEMBL8205297 0.89 HIF1A (0.50) HIF1ARXRARXRBRXRGTP53
SCHEMBL7664008 0.89 HIF1A (0.49) HIF1ARXRARXRBRXRGTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117545496-A Microorganism consortium and use thereof 生物米卡有限公司 2024-02-09 CN claimed
CN-116831993-A Freeze-dried preparation of antibacterial protein 尹特荣生物科技株式会社 2023-10-03 CN claimed
WO-2023170559-A1 METHOD AND COMPOSITION FOR IMPROVEMENT OF AGRICULTURAL PRODUCE UPL Corporation Limited (MU) 2023-09-14 WO claimed
CN-116615549-A Recombinant microorganism and use thereof 朗泽科技有限公司 2023-08-18 CN claimed
EP-3986129-B1 STABLE AQUEOUS SUSPENSION FORMULATIONS BASF SE (DE) 2023-08-09 EP claimed
CN-116349686-A Fungicidal composition containing substituted triazolinone ether compound and application thereof 沈阳中化农药化工研发有限公司 2023-06-30 CN claimed
CN-115403600-A Preparation method of clilboro 安徽普利药业有限公司 2022-11-29 CN claimed
CN-115003686-A Medicine for resisting coronavirus infection and application thereof 四川科伦博泰生物医药股份有限公司 2022-09-02 CN claimed
CN-114086193-A Rust-removing material and preparation method and application thereof 广东财领头新材料有限公司 2022-02-25 CN claimed
CN-110887926-B Sample pretreatment method for determining residual quantity of various pesticides in dendrobium officinale and detection method thereof 浙江省农业科学院 2022-02-25 CN claimed
US-20010046978-A1 Synergistic fungicidal composition comprising a compound analogous to strobilurin DUVERT PATRICE (FR) 2001-11-29 US claimed
US-20010046492-A1 Fungicidal mixtures comprising R-metalaxyl SYNGENTA CROP PROTECTION, INC. 2001-11-29 US claimed
EP-0836385-B1 CROP PROTECTION PRODUCTS SYNGENTA PARTICIPATIONS AG (CH) 2001-07-11 EP claimed
US-20010006964-A1 Fungicidal active compound combinations BAYER INTELLECTUAL PROPERTY GMBH (DE) 2001-07-05 US claimed
EP-0712278-B1 N-PYRIDYLTOLUIDINE-CONTAINING FUNGICIDAL WATER DISPERSIBLE GRANULES ISHIHARA SANGYO KAISHA (JP) 2001-06-13 EP claimed
EP-1104990-A2 FUNGICIDAL MIXTURES COMPRISING R-METALAXYL Syngenta Participations AG (CH) 2001-06-13 EP claimed
WO-2000013505-A2 FUNGICIDAL MIXTURES COMPRISING R-METALAXYL SYNGENTA PARTICIPATIONS AG (CH) 2000-03-16 WO claimed
EP-0610764-B1 Fungicidal mixture BAYER AG (DE) 1999-05-12 EP claimed
EP-0555186-B1 Fungicidal compositions CIBA GEIGY AG (CH) 1997-11-05 EP claimed
US-5554619-A Microbicides CIBA-GEIGY CORPORATION (US) 1996-09-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010006964-A1 Fungicidal active compound combinations VAT1, CASP1, CACNA1E HIF1A 3493/4885RXRA 4598/4885RXRB 4670/4885
US-20010046978-A1 Synergistic fungicidal composition comprising a compound analogous to strobilurin CHN2, CYTH2, CNPY3 HIF1A 2945/4885RXRA 3714/4885RXRB 3427/4885
US-20010046492-A1 Fungicidal mixtures comprising R-metalaxyl O60361, PNMT, PMM2 HIF1A 4691/4885RXRA 4125/4885RXRB 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.