Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 8/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.36 |
| ▸ | ELOC | Q15369 | 1/20 | 0.36 |
| ▸ | ELOB | Q15370 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666520 | 0.76 | VHL (0.42) | SRD5A1VHLELOCELOBKMT2A | |
| SCHEMBL6979036 | 0.71 | SRD5A1 (0.47) | SRD5A1VHLELOCELOBKMT2A | |
| SCHEMBL7663992 | 0.70 | P2RX4 (0.41) | SRD5A1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL69760 | 0.67 | OPRK1 (0.48) | SRD5A1VHLELOCELOBKMT2A | |
| SCHEMBL10493802 | 0.67 | SRD5A1 (0.46) | SRD5A1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL11139328 | 0.65 | VHL (0.41) | SRD5A1VHLELOCELOBKMT2A | |
| SCHEMBL11141196 | 0.64 | NOTUM (0.48) | SRD5A1VHLELOCELOBKMT2A | |
| SCHEMBL11147651 | 0.63 | NOTUM (0.66) | — | |
| SCHEMBL9538299 | 0.63 | ALDH1A1 (0.49) | SRD5A1VHLELOCELOBKMT2A | |
| SCHEMBL18637228 | 0.62 | AHR (0.54) | KMT2AAHRKDM4EALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |