Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717839 | 0.65 | NPC1 (0.50) | CRBN | |
| SCHEMBL31001777 | 0.65 | CRBN (0.34) | CRBNDDB1 | |
| SCHEMBL21929908 | 0.63 | CRBN (0.36) | CRBNDDB1 | |
| SCHEMBL7719444 | 0.62 | PLAT (0.47) | CRBNDDB1 | |
| SCHEMBL31001871 | 0.62 | PLAT (0.50) | CRBN | |
| SCHEMBL24184143 | 0.62 | CRBN (0.35) | CRBN | |
| SCHEMBL3785293 | 0.62 | PLAT (0.47) | — | |
| SCHEMBL31001803 | 0.62 | HCAR1 (0.36) | CRBNDDB1 | |
| SCHEMBL28948286 | 0.62 | PLAT (0.42) | CRBNDDB1 | |
| SCHEMBL14269847 | 0.62 | CRBN (0.38) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384327-B1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-6492377-B1 | Imidazotriazolopyrimidines with adenosine-antagonistic activity | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |
| US-4160017-A | EMETIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |