Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725392 | 0.98 | HDAC1 (0.40) | HDAC1HDAC2LTA4HNR5A1ESR2 | |
| SCHEMBL9146595 | 0.95 | LTA4H (0.43) | LTA4HNR5A1ESR2ESR1APP | |
| SCHEMBL8729533 | 0.84 | HDAC1 (0.44) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9141866 | 0.83 | NR5A1 (0.50) | HDAC1HDAC2LTA4HNR5A1APP | |
| SCHEMBL9144611 | 0.83 | USP2 (0.45) | LTA4HNR5A1ESR2ESR1KIF11 | |
| SCHEMBL8724593 | 0.82 | HDAC1 (0.43) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9187863 | 0.81 | RARB (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7661281 | 0.81 | CHRNB2 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7673767 | 0.80 | HDAC1 (0.40) | HDAC1HDAC2KIF11HDAC3HDAC4 | |
| SCHEMBL9146037 | 0.79 | ESR2 (0.41) | LTA4HNR5A1ESR2ESR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388146-B1 | AROMATIC UNSATURATED NOMONER | SHARP KABUSHIKI KAISHA (JP) | 2002-05-14 | — | — | US | disclosed |
| US-5814378-A | ACRYLATED ESTER OF A BIPHENYL COMPOUND | SHARP KABUSHIKI KAISHA (JP) | 1998-09-29 | — | — | US | disclosed |