Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23178724 | 0.97 | MAOB (0.46) | MAOBMAOAAR | |
| SCHEMBL84221 | 0.87 | TAAR1 (0.43) | MAOBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL23178723 | 0.86 | ALDH1A1 (0.47) | MAOBMAOAALDH1A1MAPTNPC1 | |
| SCHEMBL23178745 | 0.85 | ALDH1A1 (0.39) | MAOBMAOAALDH1A1MAPTNPC1 | |
| SCHEMBL23178721 | 0.84 | TAAR1 (0.41) | MAOBMAOAALDH1A1MAPTNPC1 | |
| SCHEMBL23178728 | 0.84 | NPC1 (0.41) | MAOBMAOAALDH1A1MAPTNPC1 | |
| SCHEMBL24274919 | 0.84 | MAOB (0.43) | MAOBMAOAALDH1A1MAPTNPC1 | |
| SCHEMBL31323933 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL23178722 | 0.81 | ALOX5 (0.45) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8693966 | 0.81 | ALOX5 (0.42) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414000-B1 | A 2-OXAZOLINE COMPOUND CONTAINING PHENYL RINGS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-02 | — | — | US | disclosed |