SCHEMBL7664620

CN1CC[C@]23c4c5ccc(OC(=O)c6ccccc6)c4O[C@H]2[C@@H](OS(=O)(=O)O)C=C[C@H]3[C@H]1C5

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	13/20	1.00

▸	OPRM1	P35372	6/20	0.61

▸	OPRK1	P41145	6/20	0.61

▸	MRGPRX2	Q96LB1	2/20	0.55

▸	ADRB1	P08588	1/20	0.55

▸	PDE4D	Q08499	1/20	0.55

▸	PDE3A	Q14432	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15734537	0.90	OPRD1 (0.82)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL1556900	0.90	OPRD1 (0.82)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL7664770	0.90	OPRD1 (1.00)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL7675601	0.87	OPRD1 (1.00)	OPRD1OPRM1OPRK1
SCHEMBL7668879	0.87	OPRD1 (1.00)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL7671146	0.87	OPRD1 (1.00)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL6459794	0.87	OPRD1 (0.77)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL30345074	0.87	OPRD1 (1.00)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL29846200	0.87	OPRD1 (0.87)	OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL12085066	0.85	OPRD1 (0.73)	OPRD1OPRM1OPRK1MRGPRX2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6403602-B1	Morphine-6-sulfate analogues and their use for the treatment of pain	THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION	2002-06-11	—	—	US	disclosed