Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.73 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.73 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12082084 | 0.96 | OPRD1 (0.76) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082085 | 0.95 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL15501040 | 0.95 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082398 | 0.93 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL15702077 | 0.92 | OPRD1 (0.71) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082393 | 0.92 | OPRD1 (0.74) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082396 | 0.92 | OPRD1 (0.70) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Quinoline SCHEMBL27880973 | 0.91 | OPRD1 (0.65) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL28475957 | 0.91 | OPRD1 (0.67) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL27496008 | 0.90 | OPRD1 (0.66) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863513-B | Abuse-proofed dosage form | GRUENENTHAL GMBH | 2013-01-16 | — | — | CN | disclosed |
| CN-1980643-B | Method for producing abuse-proofed solid dosage forms | GRUENENTHAL GMBH | 2012-05-30 | — | — | CN | disclosed |
| CN-100577150-C | Abuse-proof dosage form | GRUENENTHAL GMBH | 2010-01-06 | — | — | CN | disclosed |
| CN-101421391-A | High yield activation of polymer surfaces for covalent attachment of molecules | UNIV PRINCETON (US) | 2009-04-29 | — | — | CN | disclosed |
| US-6936661-B2 | Medical contact adhesive comprising a two phase adhesive matrix of polyacrylates and polyamine salts | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20040010054-A1 | Pressure sensitive adhesives; acrylated resins; transdermal administering | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2004-01-15 | — | — | US | disclosed |
| EP-1053244-B1 | GLYCOSIDATION OF 4,5-EPOXYMORPHINAN-6-OLS | FINETECH LTD (IL) | 2003-10-22 | — | — | EP | disclosed |
| US-6555665-B1 | With a thioglycoside as a glycoside donor in the presence of a thiophilic promoter; stereoselectivity, high yield; hydrolysing product to obtain Morphine-6-beta-D-glucuronide (M6G) | CENES LIMITED (GB) | 2003-04-29 | — | — | US | disclosed |
| US-6403602-B1 | Morphine-6-sulfate analogues and their use for the treatment of pain | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2002-06-11 | — | — | US | disclosed |