Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664625 | 1.00 | CNR1 (0.48) | CNR1CNR2HTTNPSR1CACNA1B | |
| SCHEMBL7661393 | 0.90 | ACHE (0.48) | NPSR1CACNA1BACHECACNA2D1CACNB1 | |
| SCHEMBL7425357 | 0.90 | ACHE (0.48) | NPSR1CACNA1BACHECACNA2D1CACNB1 | |
| SCHEMBL7661270 | 0.87 | CNR1 (0.47) | CNR1CNR2CACNA1BACHECACNA2D1 | |
| SCHEMBL7391183 | 0.87 | CNR1 (0.47) | CNR1CNR2CACNA1BACHECACNA2D1 | |
| SCHEMBL7664035 | 0.85 | CACNA2D1 (0.49) | CACNA1BACHECACNA2D1CACNB1CACNA1C | |
| SCHEMBL7390924 | 0.85 | CACNA2D1 (0.49) | CACNA1BACHECACNA2D1CACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL7653866 | 0.84 | CACNA1B (0.48) | CACNA1BACHECACNA2D1CACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL7653878 | 0.84 | CACNA1B (0.48) | CACNA1BACHECACNA2D1CACNB1CACNA1C | |
| SCHEMBL7428289 | 0.83 | CNR1 (0.54) | CNR1CNR2HTTNPSR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |