Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 1.00 |
| ▸ | HTR2C | P28335 | 8/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664636 | 1.00 | HTR2B (1.00) | HTR2BHTR2CCYP1A2CYP3A4NFKB1 | |
| Hydrochloric Acid SCHEMBL7656658 | 0.99 | HTR2B (0.98) | HTR2BHTR2CCYP1A2CYP3A4NFKB1 | |
| Hydrochloric Acid SCHEMBL7656654 | 0.99 | HTR2B (0.98) | HTR2BHTR2CCYP1A2CYP3A4NFKB1 | |
| Hydrochloric Acid SCHEMBL7658689 | 0.93 | HTR2B (0.87) | HTR2BHTR2CCYP1A2CYP3A4NFKB1 | |
| SCHEMBL7654434 | 0.88 | HTR2B (0.78) | HTR2BHTR2CCYP1A2CYP3A4NFKB1 | |
| SCHEMBL7399867 | 0.85 | HTR2C (0.74) | HTR2BHTR2CCYP1A2CYP3A4NFKB1 | |
| Hydrochloric Acid SCHEMBL7663182 | 0.84 | HTR2C (0.73) | HTR2BHTR2CNPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL7652968 | 0.82 | HTR2C (0.69) | HTR2BHTR2CNPC1RAB9ATP53 | |
| SCHEMBL8109950 | 0.80 | HTR2C (0.67) | HTR2BHTR2CTP53MAPTBLM | |
| Hydrochloric Acid SCHEMBL7660216 | 0.77 | HTR2C (0.62) | HTR2BHTR2CNPC1RAB9APLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | claimed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |