Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 2/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566543 | 0.87 | GABRA2 (0.48) | MAPK9GABRA2GABRB2MLYCDSYK | |
| SCHEMBL7665202 | 0.82 | MAPK14 (0.51) | MAPK9GABRA2GABRB2 | |
| SCHEMBL7661360 | 0.82 | GABRA2 (0.45) | MAPK9GABRA2GABRB2MLYCDSYK | |
| SCHEMBL7665192 | 0.82 | MAPK14 (0.51) | MAPK9GABRA2GABRB2 | |
| SCHEMBL7534386 | 0.82 | GABRA2 (0.48) | MAPK9GABRA2GABRB2MLYCDSYK | |
| SCHEMBL7665355 | 0.81 | GABRA2 (0.48) | MAPK9GABRA2GABRB2MLYCDSYK | |
| SCHEMBL7665100 | 0.80 | GABRA2 (0.45) | MAPK9GABRA2GABRB2MLYCDSYK | |
| SCHEMBL6986720 | 0.80 | MAPK9 (0.67) | MAPK9PIM1MAPTMAPK10 | |
| SCHEMBL6981902 | 0.78 | MAPK9 (0.62) | MAPK9PIM1MAPK10CYP3A4MAPK8 | |
| SCHEMBL7189430 | 0.77 | MAPK9 (0.63) | MAPK9PIM1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492516-B1 | PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF WHICH EXHIBIT UTILITY FOR THE TREATMENT OF CYTOKINE MEDIATED DISEASES SUCH AS ARTHRITIS. | MERCK & CO., INC. | 2002-12-10 | — | — | US | disclosed |