Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664779 | 1.00 | MEN1 (0.57) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL13256374 | 1.00 | MEN1 (0.57) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL7662999 | 0.96 | MEN1 (0.61) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL7663002 | 0.96 | MEN1 (0.61) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL15724446 | 0.93 | PTPN1 (0.49) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL15304505 | 0.92 | FOLH1 (0.49) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL16076513 | 0.91 | BLM (0.57) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL13911358 | 0.90 | PTPN1 (0.53) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL15483813 | 0.90 | MEN1 (0.44) | MEN1NPC1USP2S1PR2LMNA | |
| SCHEMBL19662368 | 0.90 | FOLH1 (0.48) | MEN1NPC1USP2S1PR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112254-B1 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PROD INC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-6437141-B2 | FOR LABELING TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-20010020098-A1 | For labeling target molecules | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-09-06 | — | — | US | disclosed |
| US-6224644-B1 | CYANINE DYES INCLUDES FREE OR PROTECTED THIOL, AMINE OR HYDROXY SUBSTITUENT CAPABLE OF REACTING WITH A TARGET MOLECULE THROUGH A NEUCLOPHILIC DISPLACEMENT, USEFUL IN LABELING A VARIETY OF TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6204389-B1 | DEBLOCKING; NUCLEOPHILIC DISPLACEMENT | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6197956-B1 | FLUORESCENT BENZIMIDAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, BENZOTHIAZINE, BENZOXAZINE AND QUINOLINE DYES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-06 | — | — | US | disclosed |
| US-6114350-A | Cyanine dyes and synthesis methods thereof | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020098-A1 | For labeling target molecules | CYC1, THEM6, TPH1 | MEN1 1688/4885NPC1 2120/4885USP2 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.