Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 14/20 | 0.48 |
| ▸ | PPARA | Q07869 | 13/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665010 | 1.00 | NPC1 (0.50) | NPC1RAB9APPARGPPARAL3MBTL1 | |
| SCHEMBL7671289 | 0.87 | PPARG (0.48) | NPC1RAB9APPARGPPARAL3MBTL1 | |
| SCHEMBL7671293 | 0.87 | PPARG (0.48) | NPC1RAB9APPARGPPARAL3MBTL1 | |
| SCHEMBL7673517 | 0.86 | NPC1 (0.42) | NPC1RAB9APPARGPPARAL3MBTL1 | |
| SCHEMBL7673511 | 0.86 | NPC1 (0.42) | NPC1RAB9APPARGPPARAL3MBTL1 | |
| SCHEMBL7668909 | 0.85 | TP53 (0.37) | NPC1RAB9AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7669055 | 0.75 | HPGD (0.45) | L3MBTL1LMNAHTTTP53 | |
| SCHEMBL7671067 | 0.73 | PPARG (0.39) | NPC1RAB9APPARGPPARAL3MBTL1 | |
| SCHEMBL7671070 | 0.73 | PPARG (0.39) | NPC1RAB9APPARGPPARAL3MBTL1 | |
| SCHEMBL7673230 | 0.73 | PPARG (0.60) | NPC1RAB9APPARGPPARAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |