Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665010 | 0.85 | NPC1 (0.50) | TP53LMNANPC1RAB9AHTT | |
| SCHEMBL7665012 | 0.85 | NPC1 (0.50) | TP53LMNANPC1RAB9AHTT | |
| SCHEMBL7669055 | 0.75 | HPGD (0.45) | TP53MAPTLMNAALDH1A1TSHR | |
| SCHEMBL7671289 | 0.72 | PPARG (0.48) | LMNANPC1RAB9AALDH1A1HTT | |
| SCHEMBL7671293 | 0.72 | PPARG (0.48) | LMNANPC1RAB9AALDH1A1HTT | |
| SCHEMBL27761176 | 0.66 | MAOB (0.46) | LMNANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL25890135 | 0.66 | NPC1 (0.42) | TP53MAPTLMNANPC1RAB9A | |
| SCHEMBL7667380 | 0.65 | CA2 (0.43) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11274824 | 0.64 | NPC1 (0.45) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL2050802 | 0.64 | NPC1 (0.47) | MAPTLMNANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |