Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669294 | 0.81 | MEN1 (0.44) | HPGDADORA3MAPTALDH1A1CYP11B1 | |
| SCHEMBL7667782 | 0.80 | HPGD (0.43) | HPGDMAPTHTTNPSR1LMNA | |
| SCHEMBL7690530 | 0.77 | AVPR2 (0.44) | MAPTALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL7668909 | 0.75 | TP53 (0.37) | HPGDMAPTALDH1A1KDM4EKDM4A | |
| SCHEMBL7665010 | 0.75 | NPC1 (0.50) | HTTL3MBTL1LMNATP53 | |
| SCHEMBL7665012 | 0.75 | NPC1 (0.50) | HTTL3MBTL1LMNATP53 | |
| SCHEMBL23902474 | 0.73 | CYP11B1 (0.51) | KDM4ACYP11B1CYP11B2CYP19A1BACE1 | |
| SCHEMBL9354103 | 0.71 | ALDH1A1 (0.55) | HPGDMAPTALDH1A1KDM4EKDM4A | |
| SCHEMBL25275352 | 0.71 | GSK3B (0.50) | HPGDADORA3MAPTALDH1A1KDM4E | |
| SCHEMBL7660231 | 0.71 | MEN1 (0.41) | HPGDMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |