Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581950 | 0.83 | — | — | |
| SCHEMBL6583629 | 0.73 | GRIA1 (0.39) | — | |
| SCHEMBL6581994 | 0.71 | FABP6 (0.37) | TYMS | |
| SCHEMBL6579702 | 0.70 | ALDH1A1 (0.48) | TYMS | |
| SCHEMBL6583429 | 0.65 | PSMB8 (0.36) | — | |
| SCHEMBL6584955 | 0.63 | — | — | |
| SCHEMBL7665471 | 0.61 | HTR1D (0.39) | — | |
| SCHEMBL6583425 | 0.60 | GRIN2D (0.45) | — | |
| SCHEMBL6142558 | 0.60 | TDP1 (0.46) | TYMS | |
| SCHEMBL6579436 | 0.59 | TACR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486190-B1 | 5-(2-imidazolinylamino)-benzimidazole derivatives, their preparation and their use as .alpha.-adrenoceptor agonists with improved metabolic stability | THE PROCTER & GAMBLE COMPANY | 2002-11-26 | — | — | US | disclosed |