SCHEMBL7665659

SCHEMBL7665659

CS/C(=C\[N+](=O)[O-])Nc1ccc(Cl)nc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.70
MAPT P10636 8/20 0.70
HTT P42858 2/20 0.70
LMNA P02545 3/20 0.63
SMN1; SMN2 Q16637 2/20 0.54
KCNQ3 O43525 10/20 0.43
KCNQ2 O43526 10/20 0.43
KCNE1 P15382 6/20 0.43
KCNQ1 P51787 6/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
BACE1 P56817 1/20 0.42
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7665664 1.00 ALDH1A1 (0.70) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL22309920 0.80 ALDH1A1 (1.00) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL7663631 0.80 ALDH1A1 (0.50) ALDH1A1MAPTHTTLMNAKCNQ3
SCHEMBL7663627 0.80 ALDH1A1 (0.50) ALDH1A1MAPTHTTLMNAKCNQ3
SCHEMBL7688471 0.78 KCNQ3 (0.43) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL7688470 0.78 KCNQ3 (0.43) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL1562969 0.78 MAPT (1.00) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL1562970 0.78 MAPT (1.00) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL7667286 0.78 ALDH1A1 (0.48) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL7667283 0.78 ALDH1A1 (0.48) ALDH1A1MAPTHTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0366085-B1 Tetrahydropyrimidines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-04-17 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
US-5084459-A Insecticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-01-28 US disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed