SCHEMBL7667286

SCHEMBL7667286

CSC(=C[N+](=O)[O-])NCc1ccc(Cl)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.48
MAPT P10636 8/20 0.48
HTT P42858 2/20 0.48
NAMPT P43490 2/20 0.43
CYP2C9 P11712 2/20 0.43
FAAH O00519 1/20 0.43
LMNA P02545 2/20 0.43
CHRNB2 P17787 2/20 0.41
CHRNA4 P43681 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
CHRNA1 P02708 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA7 P36544 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7667283 1.00 ALDH1A1 (0.48) ALDH1A1MAPTHTTNAMPTCYP2C9
SCHEMBL9046373 0.85 ALDH1A1 (0.44) ALDH1A1MAPTHTTNAMPTLMNA
SCHEMBL7663609 0.83 CYP2C9 (0.44) ALDH1A1MAPTNAMPTCYP2C9FAAH
SCHEMBL7665411 0.83 ALDH1A1 (0.65) ALDH1A1MAPTHTTCYP2C9LMNA
SCHEMBL7665405 0.83 ALDH1A1 (0.65) ALDH1A1MAPTHTTCYP2C9LMNA
SCHEMBL10354495 0.82 ALDH1A1 (0.41) ALDH1A1MAPTHTTCYP2C9LMNA
SCHEMBL10354496 0.82 ALDH1A1 (0.41) ALDH1A1MAPTHTTCYP2C9LMNA
SCHEMBL9047024 0.82 FPR2 (0.44) ALDH1A1MAPTNAMPTCYP2C9FAAH
SCHEMBL9047032 0.82 FPR2 (0.44) ALDH1A1MAPTNAMPTCYP2C9FAAH
SCHEMBL9044324 0.81 MAPT (0.48) ALDH1A1MAPTHTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3007206-A None JP disclosed
JP-4187605-A None JP disclosed
JP-3047106-A None JP disclosed
JP-2191253-A None JP disclosed
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
EP-0632957-B1 A method of killing noxious insects BAYER AGROCHEM KK (JP) 2001-01-17 EP disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
CN-1044071-C Insecticidal agents NIHON TOKUSHU NOYAKU SEIZO KK (JP) 1999-07-14 CN disclosed
US-5882670-A MUSHROOM-CARRYING CRUSHED OR GROUND BROAD LEAVED TREE ATTRACTANT NIHON BAYER AGROCHEM K.K. (JP) 1999-03-16 US disclosed
US-5084467-A INSECTICIDALLY ACTIVE NITRO GUANIDINE COMPOUNDS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1992-01-28 US disclosed
US-5084459-A Insecticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-01-28 US disclosed
JP-H0347106-A INSECTICIDAL AND BACTERICIDAL COMPOSITION FOR AGRICULTURAL USE NIPPON TOKUSHU NOYAKU SEIZO KK 1991-02-28 JP disclosed
JP-H037206-A INSECTICIDAL COMPOSITION NIPPON TOKUSHU NOYAKU SEIZO KK 1991-01-14 JP disclosed
EP-0402717-A1 5-nitro-tetrahydropyrimidines and insecticides containing them for agricultural uses NIHON BAYER AGROCHEM K.K. (JP) 1990-12-19 EP disclosed
EP-0383091-A1 Insecticidally active nitro compounds NIHON BAYER AGROCHEM K.K. (JP) 1990-08-22 EP disclosed
JP-H02191253-A INSECTICIDAL NITRO COMPOUND NIPPON TOKUSHU NOYAKU SEIZO KK 1990-07-27 JP disclosed
EP-0366085-A2 Tetrahydropyrimidines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-05-02 EP disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed
JP-H00347106-A 0001-01-01 JP disclosed