SCHEMBL5151209

SCHEMBL5151209

Cc1cc(C(O)(c2ccc(OC(F)(F)F)cc2)C(F)(F)F)ccc1NC(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.42
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
EPHX2 P34913 2/20 0.38
IDH1 O75874 2/20 0.38
KCNQ3 O43525 1/20 0.38
KCNQ2 O43526 1/20 0.38
NR1H4 Q96RI1 1/20 0.37
PDE2A O00408 1/20 0.37
CISD2 Q8N5K1 1/20 0.37
DHODH Q02127 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5151216 0.92 RXFP1 (0.38) TRPV1SMN1; SMN2RXFP1CISD2
SCHEMBL5154485 0.87 SMN1; SMN2 (0.43) LMNAMAPK1SMN1; SMN2RXFP1NPC1
SCHEMBL7665668 0.85 KCNQ3 (0.46) TRPV1SMN1; SMN2RXFP1EPHX2KCNQ3
SCHEMBL29803307 0.79 RXFP1 (0.55) MEN1LMNAKMT2ASMN1; SMN2RXFP1
SCHEMBL7667607 0.79 RXFP1 (0.55) MEN1LMNAKMT2ASMN1; SMN2RXFP1
SCHEMBL5149049 0.78 RXFP1 (0.36) SMN1; SMN2RXFP1PDE2ACISD2
SCHEMBL6243514 0.77 RXFP1 (0.41) MEN1LMNAMAPK1KMT2ASMN1; SMN2
SCHEMBL29803357 0.76 SMN1; SMN2 (0.47) MEN1LMNAKMT2ASMN1; SMN2RXFP1
SCHEMBL18703070 0.76 SMN1; SMN2 (0.47) MEN1LMNAKMT2ASMN1; SMN2RXFP1
SCHEMBL7794191 0.75 CYP17A1 (0.49) TRPV1SMN1; SMN2RXFP1EPHX2IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US disclosed
EP-1671941-A1 SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent L3MBTL1, L3MBTL3, L3MBTL4 TRPV1 31/4885MEN1 4633/4885LMNA 1667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.