Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699716 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10HPGDNPC1 | |
| SCHEMBL9726590 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL3382629 | 0.83 | KDM4E (0.72) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL31074983 | 0.82 | NPC1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL341330 | 0.82 | NPC1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL5011915 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDNPC1 | |
| SCHEMBL28117577 | 0.82 | CXCR5 (0.50) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL11550861 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL305252 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL18739643 | 0.82 | HSD17B10 (0.55) | ALDH1A1KDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924556-A | Spherical magnesium halide adduct and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924555-A | Catalyst component, catalyst system, application of catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-6380396-B1 | CHEMICAL INTERMEDIATES FOR ANTIINFLAMMATORY AGENTS | PFIZER INC. | 2002-04-30 | — | — | US | disclosed |
| US-6207678-B1 | USED FOR TREATING INFLAMMATORY DISEASE SUCH AS ARTHRITIS, PSORIASIS, ASTHMA OR INFLAMMATORY BOWEL DISEASE, CENTRAL NERVOUS SYSTEM DISORDER SUCH AS ANXIETY, DEPRESSION, DEMENTIA OR PSYCHOSIS, GASTROINTESTINAL DISORDERS | PFIZER INC | 2001-03-27 | — | — | US | disclosed |