Sugi Predict

Sugi Predict / Compounds / SCHEMBL341330

SCHEMBL341330

SCHEMBL341330

COc1cccc(C(=O)Cl)c1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 4/20 0.53
▸ RAB9A P51151 4/20 0.53
▸ SMN1; SMN2 Q16637 3/20 0.53
▸ TP53 P04637 2/20 0.53
▸ HPGD P15428 1/20 0.53
▸ CNR2 P34972 1/20 0.52
▸ KMT2A Q03164 3/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ ALDH1A1 P00352 4/20 0.51
▸ POLB P06746 3/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ GAA P10253 3/20 0.50
▸ MAPT P10636 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ NFE2L2 Q16236 1/20 0.49
▸ CTSD P07339 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31074983 1.00 NPC1 (0.53) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL4776927 0.90 CNR2 (0.45) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL699716 0.88 ALDH1A1 (0.45) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL8658218 0.86 MAPK1 (0.58) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL11551244 0.84 KMT2A (0.50) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL7428124 0.84 CTSD (0.46) NPC1RAB9AHPGDCNR2ALDH1A1
SCHEMBL3762150 0.84 RAB9A (0.55) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL152563 0.82 MAPT (0.59) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL6964175 0.82 RAB9A (0.58) NPC1RAB9ASMN1; SMN2TP53HPGD
SCHEMBL29603325 0.82 MAPT (0.59) NPC1RAB9ASMN1; SMN2TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110396116-A Ketone-imidazoline -2- imine ligand [N, O] bidentate nickel, palladium complex and the preparation method and application thereof UNIV NATIONAL DONG HWA 2019-11-01 — — CN claimed
CN-109369592-A A kind of synthetic method of sweet orange flavones 陕西嘉禾生物科技股份有限公司 2019-02-22 — — CN claimed
CN-108794327-A The preparation method of 2,6-dimethoxy-benzoyl chlorides 上海华堇生物技术有限责任公司 2018-11-13 — — CN claimed
CN-107892657-A A kind of synthetic method of Itopride Hydrochloride 安徽修制药有限公司 2018-04-10 — — CN claimed
CN-107840792-A A kind of synthetic method of resveratrol 常州大学 2018-03-27 — — CN claimed
CN-103896911-A 2-(3,4-Dimethoxy)benzoyl-5-(4-substituted phenylethynyl) thiophene as well as preparation method and application thereof UNIV SOUTHERN MEDICAL 2014-07-02 — — CN claimed
CN-103073446-A Preparation method of itopride hydrochloride ZHUHAI BONDED AREA LIZHU SYNTHESIS PHARMACEUTICAL CO LTD 2013-05-01 — — CN claimed
CN-102993038-A Preparation method of itopride hydrochloride DISHA PHARMACEUTICAL GROUP CO 2013-03-27 — — CN claimed
CN-102838580-A Preparation method of mango aglycone UNIV KUNMING SCIENCE & TECHNOLOGY 2012-12-26 — — CN claimed
CN-102070549-B 5-substituted-2-(4-substituted phenyl)benzoxazole derivatives and preparation method and application thereof UNIV SHANDONG 2012-10-03 — — CN claimed
CN-102603827-A Paeoniflorin aromatic ester derivative, preparation method and applications thereof WEI WEI 2012-07-25 — — CN claimed
CN-102070549-A 5-substituted-2-(4-substituted phenyl)benzoxazole derivatives and preparation method and application thereof UNIV SHANDONG 2011-05-25 — — CN claimed
CN-101607945-A A kind of pH fluorescent probe and synthetic method thereof of wide in range responding range UNIV SHANDONG NORMAL (CN) 2009-12-23 — — CN claimed
CN-101580507-A Novel antitumor compound and preparation method and application thereof UNIV EAST CHINA SCIENCE & TECH (CN) 2009-11-18 — — CN claimed
CN-1305837-C Improved prepn process of itopride medicine material NEW MEDICINE DEV CT JILIN XIUZ (CN) 2007-03-21 — — CN claimed
CN-1706815-A Improved prepn process of itopride medicine material NEW MEDICINE DEV CT JILIN XIUZ (CN) 2005-12-14 — — CN claimed
US-4543213-A SEQUESTERING AGENTS FOR PLUTONIUM THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1985-09-24 — — US claimed
US-12173018-B2 Penicillin-binding protein inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2024-12-24 — — US disclosed
US-4181654-A SEQUESTERING AGENTS FOR ACTINIDE(IV) IONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1980-01-01 — — US disclosed
US-4058523-A ANTIULCER, VASODILATION, HYPOTENSIVE, ANALGESIC CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1977-11-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12173018-B2 Penicillin-binding protein inhibitors PEPD, BPGM, EBPL NPC1 3502/4885RAB9A 1980/4885SMN1; SMN2 3101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.