Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548607 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL1817688 | 0.85 | RAB9A (0.64) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL840217 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL27614147 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL1818695 | 0.84 | NPSR1 (0.61) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL12615067 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL1742555 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL2545099 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL10391003 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A | |
| SCHEMBL8868314 | 0.83 | AOC3 (0.56) | ALDH1A1HSD17B10CYP1A2NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |