SCHEMBL7666643

SCHEMBL7666643

CCCCCOC[C@H](C)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.70
USP2 O75604 1/20 0.61
HTT P42858 2/20 0.59
SPHK1 Q9NYA1 1/20 0.58
TDP1 Q9NUW8 1/20 0.52
LPAR5 Q9H1C0 4/20 0.50
PRKD3 O94806 1/20 0.47
PRKCG P05129 1/20 0.47
PRKCB P05771 1/20 0.47
PRKCA P17252 1/20 0.47
PRKCH P24723 1/20 0.47
PRKCI P41743 1/20 0.47
PRKCE Q02156 1/20 0.47
PRKCQ Q04759 1/20 0.47
PRKCZ Q05513 1/20 0.47
PRKCD Q05655 1/20 0.47
PRKD1 Q15139 1/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7149906 1.00 HSD17B10 (0.70) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL535931 1.00 HSD17B10 (0.70) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL9637036 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL1091934 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL7661581 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL10745894 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL7549303 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL15070143 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL21046009 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1
SCHEMBL186489 0.98 HSD17B10 (0.67) HSD17B10USP2HTTSPHK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3787402-A1 EMULSIFIABLE CONCENTRATES Dow Global Technologies, LLC (US) 2021-03-10 EP disclosed
US-6384228-B2 EPIBATIDINE; ANALGESICS; ANIMAL EXTRACTS NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-05-07 US disclosed
US-20020010339-A1 METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-01-24 US disclosed
EP-0301587-B1 LIQUID CRYSTAL COMPOUNDS AND INTERMEDIATES THEREOF WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-15 EP disclosed
US-5114615-A Compounds for optical apparatus WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-05-19 US disclosed
EP-0301587-A1 Liquid crystal compounds and intermediates thereof WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1989-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010339-A1 METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF DHPS, ALAD, HAAO HSD17B10 154/4885USP2 2560/4885HTT 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.