Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671810 | 0.82 | CYP19A1 (0.46) | CYP19A1PTPN1 | |
| SCHEMBL7079785 | 0.79 | CYP19A1 (0.56) | CYP19A1LMNAKMT2A | |
| SCHEMBL7674614 | 0.78 | CYP19A1 (0.59) | CYP19A1LMNAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL12150535 | 0.77 | LMNA (0.62) | LMNAKMT2APTPN1PTPN2PTPN6 | |
| SCHEMBL6480011 | 0.77 | LMNA (0.62) | LMNAKMT2ASMN1; SMN2PTPN1PTPN2 | |
| SCHEMBL7081335 | 0.77 | ALDH1A1 (0.46) | CYP19A1LMNAKMT2ASMN1; SMN2TBXAS1 | |
| SCHEMBL7081122 | 0.77 | CYP19A1 (0.39) | CYP19A1LMNAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7081463 | 0.76 | LMNA (0.49) | LMNAKMT2AMAPT | |
| SCHEMBL7085127 | 0.73 | LMNA (0.61) | LMNAKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15043256 | 0.73 | LMNA (0.61) | LMNAKMT2AFYNSMN1; SMN2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380249-B1 | HIV integrase inhibitors | MERCK & CO., INC. | 2002-04-30 | — | — | US | disclosed |