Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660361 | 0.81 | EPHX2 (0.54) | P2RX7MEN1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL7607645 | 0.81 | HRH3 (0.43) | SUV39H2PIM1PIM3PIM2HRH3 | |
| SCHEMBL7242505 | 0.76 | SUV39H2 (0.50) | SUV39H2PIM1PIM3PIM2 | |
| SCHEMBL6486070 | 0.76 | SUV39H2 (0.50) | SUV39H2PIM1PIM3PIM2 | |
| SCHEMBL25453975 | 0.75 | SUV39H2 (0.55) | SUV39H2PIM1PIM3PIM2 | |
| SCHEMBL1350982 | 0.74 | SUV39H2 (0.48) | SUV39H2PIM1PIM3PIM2 | |
| SCHEMBL1350984 | 0.74 | SUV39H2 (0.48) | SUV39H2PIM1PIM3PIM2 | |
| SCHEMBL7235725 | 0.74 | SUV39H2 (0.48) | SUV39H2PIM1PIM3PIM2 | |
| SCHEMBL4508024 | 0.73 | P2RX7 (0.50) | P2RX7EPHX1 | |
| SCHEMBL30371860 | 0.73 | RAD52 (0.58) | MEN1ALDH1A1KMT2ANPSR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492355-B1 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |