Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | CCR9 | P51686 | 4/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383795 | 0.87 | CYP2C9 (0.69) | CYP1A2CYP2C9FFAR4CCR9KCNA5 | |
| SCHEMBL23200315 | 0.86 | LMNA (0.76) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL31138238 | 0.86 | LMNA (0.76) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL24490698 | 0.80 | POLB (0.49) | LMNAGAAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3512980 | 0.77 | CYP2C9 (0.72) | LMNAHTTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL31138312 | 0.77 | FFAR4 (0.65) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL23200363 | 0.77 | FFAR4 (0.65) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL7589382 | 0.77 | FFAR4 (0.71) | GAAALDH1A1SMN1; SMN2CYP2C9FFAR4 | |
| SCHEMBL3511736 | 0.76 | CYP2C9 (0.64) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL3513141 | 0.76 | CYP2C9 (0.60) | LMNAHTTGAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |