Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CCR9 | P51686 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591561 | 0.86 | FFAR4 (0.64) | FFAR4ALDH1A1GAASMN1; SMN2CCR9 | |
| SCHEMBL14601690 | 0.84 | FFAR4 (0.68) | FFAR4ALDH1A1GFERNPY5RRORC | |
| SCHEMBL6756075 | 0.84 | FFAR4 (0.68) | FFAR4ALDH1A1GFERNPY5RRORC | |
| SCHEMBL7595414 | 0.83 | ALDH1A1 (0.70) | FFAR4ALDH1A1GAAGFERCYP2C9 | |
| SCHEMBL7569763 | 0.81 | FFAR4 (0.59) | FFAR4GAAMAPTCCR9 | |
| SCHEMBL7590053 | 0.81 | FFAR4 (0.59) | FFAR4GAASMN1; SMN2MAPTCCR9 | |
| SCHEMBL26536700 | 0.81 | PKM (0.70) | FFAR4NPY5RRORCSMN1; SMN2MAPT | |
| SCHEMBL7577285 | 0.81 | FFAR4 (0.59) | FFAR4ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL7591880 | 0.81 | SLC40A1 (0.61) | FFAR4ALDH1A1RORCMAPT | |
| SCHEMBL7383795 | 0.80 | CYP2C9 (0.69) | FFAR4CYP2C9CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |