Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 14/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661700 | 0.91 | CMA1 (0.58) | CMA1ELANECTSGCTRC | |
| SCHEMBL7661080 | 0.90 | CCR1 (0.46) | CMA1ELANECCR1 | |
| SCHEMBL7660620 | 0.88 | CTSD (0.45) | CMA1ELANECCR1 | |
| SCHEMBL7665870 | 0.85 | CTSD (0.46) | CMA1CCR1 | |
| SCHEMBL7669892 | 0.84 | CCR1 (0.47) | ELANECCR1 | |
| SCHEMBL7670856 | 0.84 | CCR1 (0.52) | ELANECCR1 | |
| SCHEMBL7665212 | 0.84 | F2 (0.42) | CMA1ELANECCR1 | |
| SCHEMBL7662788 | 0.83 | CMA1 (0.56) | CMA1ELANECTSGCTRC | |
| SCHEMBL7662793 | 0.83 | CMA1 (0.56) | CMA1ELANECTSGCTRC | |
| SCHEMBL7665808 | 0.83 | CAPN1 (0.41) | CMA1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |