Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664353 | 0.91 | CMA1 (0.45) | MMP1MMP2MMP3MMP7CMA1 | |
| SCHEMBL7665212 | 0.88 | F2 (0.42) | CAPN1CCR1MMP2MMP3MMP7 | |
| SCHEMBL7670720 | 0.86 | PRSS8 (0.47) | CYP3A4CTSS | |
| SCHEMBL7665843 | 0.85 | CTSD (0.41) | CAPN1CCR1CTSBCTSKCTSL | |
| SCHEMBL7661080 | 0.85 | CCR1 (0.46) | CAPN1CCR1CTSBCTSKCMA1 | |
| SCHEMBL5711332 | 0.85 | CAPN1 (0.46) | CAPN1CCR1MMP1MMP2MMP3 | |
| SCHEMBL7667642 | 0.83 | CMA1 (0.51) | CCR1CMA1 | |
| SCHEMBL7661632 | 0.82 | F2 (0.43) | CAPN1CCR1CTSBCTSKCMA1 | |
| SCHEMBL7665870 | 0.81 | CTSD (0.46) | CAPN1CCR1CTSBCTSKCMA1 | |
| SCHEMBL7661037 | 0.80 | CTSD (0.41) | CAPN1CCR1CTSBCTSKCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |