Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667709 | 0.83 | PTGS2 (0.39) | TBXAS1KDM4EPOLBPTGS2AHR | |
| SCHEMBL7667718 | 0.82 | CYP19A1 (0.40) | TBXAS1KDM4EPOLBPTGS2AHR | |
| SCHEMBL7657854 | 0.74 | FNTA (0.49) | NPSR1 | |
| SCHEMBL7664949 | 0.73 | PTGS2 (0.40) | POLBPTGS2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7562813 | 0.72 | MEN1 (0.50) | KDM4EGAANPC1 | |
| SCHEMBL7664955 | 0.72 | CYP19A1 (0.45) | TBXAS1POLBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7563958 | 0.70 | TSHR (0.49) | KDM4EGAANPC1 | |
| SCHEMBL7567992 | 0.70 | MAPT (0.47) | KDM4ENPSR1GAA | |
| SCHEMBL7568524 | 0.70 | PTGS2 (0.50) | TBXAS1PTGS2NPSR1CYP19A1GAA | |
| SCHEMBL9368529 | 0.69 | CYP19A1 (0.52) | TBXAS1KDM4EPOLBPTGS2CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | disclosed |