Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 6/20 | 0.60 |
| ▸ | DRD4 | P21917 | 5/20 | 0.60 |
| ▸ | DRD3 | P35462 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856027 | 0.88 | BCHE (0.79) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL10463380 | 0.75 | LMNA (0.97) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL1849016 | 0.75 | LMNA (0.90) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL29992486 | 0.75 | HTR2A (0.76) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL734052 | 0.75 | HTR2A (0.76) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL11838124 | 0.74 | BCHE (0.84) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL948662 | 0.74 | HTR6 (1.00) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL8789790 | 0.74 | LMNA (1.00) | BCHECYP2D6DRD2DRD4DRD3 | |
| SCHEMBL23964192 | 0.73 | DRD4 (0.80) | BCHECYP2D6DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL28260331 | 0.73 | HTR6 (0.97) | BCHECYP2D6DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407106-B1 | FOR THERAPY OF INFLAMMATORY DISTURBANCES OF THE GASTROINTESTINAL TRACT | SOLVAY PHARMACEUTICALS GMBH (DE) | 2002-06-18 | — | — | US | disclosed |