Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 1.00 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 1.00 |
| ▸ | PTGFR | P43088 | 7/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.79 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.79 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.79 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.79 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.79 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14140434 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7667989 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL7667980 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL19403624 | 0.91 | ALDH1A1 (0.83) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL18932898 | 0.91 | ALDH1A1 (0.83) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11494330 | 0.90 | ALDH1A1 (0.82) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL29354562 | 0.90 | ALDH1A1 (0.82) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| Dinoprost SCHEMBL23352547 | 0.89 | PTGFR (1.00) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| Dinoprost SCHEMBL18027080 | 0.89 | PTGFR (1.00) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| Dinoprost SCHEMBL25329567 | 0.89 | PTGFR (1.00) | ALDH1A1KDM4EHKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359181-B1 | THERAPY FOR VISION DEFECTS | ALLERGAN SALES, INC. | 2002-03-19 | — | — | US | disclosed |
| US-6307092-B1 | POTENT OCULAR HYPOTENSIVES AND ARE PARTICULARLY SUITED FOR THE MANAGEMENT OF GLAUCOMA. | ALLERGAN SALES, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6248783-B1 | GLAUCOMA THERAPY | ALLERGAN SALES, INC. | 2001-06-19 | — | — | US | disclosed |