SCHEMBL7668338

SCHEMBL7668338

COC(=O)C1C(C)OC(=O)N1C(C)c1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.41
GPR139 Q6DWJ6 2/20 0.39
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
CASR P41180 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
XIAP P98170 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7668249 0.90 HSD11B1 (0.40) HSD11B1GPR139LMNAGAACASR
SCHEMBL7674018 0.89 HSD11B1 (0.41) HSD11B1GPR139LMNAGAACASR
SCHEMBL7671032 0.89 HSD11B1 (0.41) HSD11B1GPR139LMNAGAACASR
SCHEMBL7667160 0.89 HSD11B1 (0.41) HSD11B1GPR139LMNAGAACASR
SCHEMBL7672054 0.87 HSD11B1 (0.39) HSD11B1GPR139LMNAGAACASR
SCHEMBL7667907 0.87 HSD11B1 (0.39) HSD11B1GPR139LMNAGAACASR
SCHEMBL7670061 0.86 GPR139 (0.39) HSD11B1GPR139CASRXIAP
SCHEMBL7672137 0.84 CYP1A2 (0.39) HSD11B1GPR139CASRXIAP
SCHEMBL7668438 0.82 GPR139 (0.39) HSD11B1GPR139CASRXIAP
SCHEMBL7673133 0.82 GPR139 (0.37) HSD11B1GPR139CASRXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6414160-B1 REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed
EP-1000937-A1 PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS UBE INDUSTRIES LIMITED (JP) 2000-05-17 EP disclosed