Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CPT1A | P50416 | 1/20 | 0.44 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668618 | 1.00 | MAPT (0.61) | MAPTSMN1; SMN2USP2RAD51GSTO1 | |
| SCHEMBL7659041 | 0.89 | ALDH1A1 (0.49) | MAPTSMN1; SMN2USP2RAD51LMNA | |
| SCHEMBL7659054 | 0.89 | ALDH1A1 (0.49) | MAPTSMN1; SMN2USP2RAD51LMNA | |
| SCHEMBL8018821 | 0.86 | MAPT (0.61) | MAPTSMN1; SMN2USP2GSTO1LMNA | |
| SCHEMBL7663344 | 0.84 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2USP2LMNAALDH1A1 | |
| SCHEMBL7663243 | 0.84 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2USP2LMNAALDH1A1 | |
| SCHEMBL7661355 | 0.84 | ALDH1A1 (0.45) | MAPTRAD51GSTO1LMNAPOLB | |
| SCHEMBL7661342 | 0.84 | ALDH1A1 (0.45) | MAPTRAD51GSTO1LMNAPOLB | |
| SCHEMBL7659067 | 0.84 | RAD51 (0.48) | MAPTSMN1; SMN2USP2RAD51GSTO1 | |
| SCHEMBL7659006 | 0.84 | RAD51 (0.48) | MAPTSMN1; SMN2USP2RAD51GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-08-15 | — | — | US | claimed |
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-08-15 | — | — | US | disclosed |
| US-6355633-B1 | CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | FSHR, GNRHR, LHCGR | MAPT 4858/4885SMN1; SMN2 2927/4885USP2 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.