Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | CTSV | O60911 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972469 | 0.88 | KDM4E (0.70) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14668902 | 0.86 | ABCG2 (0.78) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL12285521 | 0.86 | ABCG2 (0.83) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL10171024 | 0.84 | HSD17B10 (0.53) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL10165568 | 0.82 | CDK4 (0.61) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL6976263 | 0.82 | ALDH1A1 (0.78) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL31188764 | 0.82 | ALDH1A1 (0.78) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL9709251 | 0.82 | ABCG2 (0.68) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14668878 | 0.82 | ABCG2 (0.94) | ABCG2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL22633747 | 0.81 | KDM4E (0.65) | ABCG2ALDH1A1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |